标题：Toxicological effects of nanometer titanium dioxide (nano-TiO2) on Chlamydomonas reinhardtii

作者：Chen, LZ(Chen, Lanzhou); Zhou, LN(Zhou, Lina); Liu, YD(Liu, Yongding); Deng, SQ(Deng, Songqiang); Wu, H(Wu, Hao); Wang, GH(Wang, Gaohong)

来源出版物：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 卷：84页：155-162 出版年：OCT 1 2012

摘要：The toxicological effects of nanometer titanium dioxide (nano-TiO2) on a unicellular green alga Chlamydomonas reinhardtii were assessed by investigating the changes of the physiology and cyto-ultrastructure of this species under treatment. We found that nano-TiO2 inhibited photosynthetic efficiency and cell growth, but the content of chlorophyll a content in algae did not change, while carotenoid and chlorophyll b contents increased. Malondialdehyde (MDA) content reached maximum values after 8 h exposure and then decreased to a moderately low level at 72 h. Electron microscopy images indicated that as concentrations of nano-TiO2 increased, a large number of C. reinhardtii cells were noted to be damaged: the number of chloroplasts declined, various other organelles were degraded, plasmolysis occurred, and TiO2 nanoparticles were found to be located inside cell wall and membrane. It was also noted that cell surface was surrounded by TiO2 particles, which could present an obstacle to the exchange of substances between the cell and its surrounding environment. To sum up, the effect of nano-TiO2 on C. reinhardtii included cell surface aggregation, photosynthesis inhibition, lipid peroxidation and new protein synthesis, while the response of C. reinhardtii to nano-TiO2 was a rapid process which occurs during 24 h after exposing and may relate to physiological stress system to mitigate damage.

文献类型：Article

语种：English

作者关键词：Nanometer titanium dioxide, Chlamydomonas reinhardtii, Physiological responses, Toxicological effects, Electron microscopy

扩展关键词：CYANOBACTERIUM NOSTOC SP; FRESH-WATER; PSEUDOKIRCHNERIELLA-SUBCAPITATA; SILVER NANOPARTICLES; DUNALIELLA-TERTIOLECTA; OXIDATIVE DAMAGE; TIO2 PARTICLES; GREEN-ALGAE; TOXICITY; NANOMATERIALS

通讯作者地址：Wang, GH ,Chinese Acad Sci, Inst Hydrobiol, State Key Lab Fresh Water Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China.

地址：

[Chen, Lanzhou; Liu, Yongding; Wang, Gaohong] Chinese Acad Sci, Inst Hydrobiol, State Key Lab Fresh Water Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China

[Chen, Lanzhou; Zhou, Lina; Deng, Songqiang; Wu, Hao] Wuhan Univ, Sch Resource & Environm Sci, Wuhan 430079, Peoples R China

电子邮件地址：space@ihb.ac.cn" data-ke-src=" mailto:space@ihb.ac.cn?>space@ihb.ac.cn" data-ke-src=" mailto:space@ihb.ac.cn?>space@ihb.ac.cn"space@ihb.ac.cn

学科类别：Environmental Sciences & Ecology; Toxicology

ISSN：0147-6513