科研成果
硕士生严坤的论文在SOFT MATTER刊出
发布时间:2014-03-31 10:20:20 发布者:yz 浏览次数:

标题:Coding for hydrogel organization through signal guided self-assembly 作者:Yan, Kun; Ding, Fuyuan; Bentley, William E.; Deng, Hongbing; Du, Yumin; Payne, Gregory F.; Shi, Xiao-Wen

来源出版物:SOFT MATTER 卷:10 期:3 页:465-469 DOI:10.1039/c3sm52405a 出版年:2014

摘要:Complex structured soft matter may have important applications in the field of tissue engineering and biomedicine. However, the discovery of facile methods to exquisitely manipulate the structure of soft matter remains a challenge. In this report, a multilayer hydrogel is fabricated from the stimuli-responsive aminopolysaccharide chitosan by using spatially localized and temporally controlled sequences of electrical signals. By programming the imposed cathodic input signals, chitosan hydrogels with varying layer number and thickness can be fabricated. The inputs of electrical signals induce the formation of hydrogel layers while short interruptions create interfaces between each layer. The thickness of each layer is controlled by the charge transfer (Q = integral idt) during the individual deposition step and the number of multilayers is controlled by the number of interruptions. Scanning electron micrographs (SEMs) reveal organized fibrous structures within each layer that are demarcated by compact orthogonal interlayer structures. This work demonstrates for the first time that an imposed sequence of electrical inputs can trigger the self-assembly of multilayered hydrogels and thus suggests the broader potential for creating an electrical "code" to generate complex structures in soft matter.

入藏号:WOS:000328886500007

文献类型:Article

语种:English

扩展关键词:ELECTROPHORETIC DEPOSITION; COMPOSITE COATINGS; CHITOSAN FILMS; ELECTROCHEMICAL FABRICATION; COLLAGEN MEMBRANES; ELECTRODEPOSITION; POLYELECTROLYTE; MOLECULES; RELEASE; SURFACE

通讯作者地址:Shi, Xiao-Wen;Wuhan Univ, Sch Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Peoples R China.

电子邮件地址:shixwwhu@163.com

地址:

[Yan, Kun; Ding, Fuyuan; Deng, Hongbing; Du, Yumin; Shi, Xiao-Wen] Wuhan Univ, Sch Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Peoples R China.

[Bentley, William E.; Payne, Gregory F.] Univ Maryland, Inst Biosci & Biotechnol Res, Fischell Dept Bioengn, College Pk, MD 20742 USA.

研究方向:Chemistry; Materials Science; Physics; Polymer Science

ISSN:1744-683X

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